ORIGINAL ABSTRACT

Genetically modified soybean DAS-44406-6 × FG72 was developed by conventional crossing to combine two single events: DAS-44406-6 and FG72. The soybean DAS-44406-6 × FG72 expresses the AAD-12, 2mEPSPS, PAT and HPPD W336 proteins to confer herbicide tolerance to 2,4-D-, glyphosate-, glufosinate-containing and HPPD-inhibiting herbicide products, respectively. The GMO Panel previously assessed the two single soybean events and did not identify safety concerns. No new data on the single soybean events were identified that could lead to modification of the original conclusions on their safety. The molecular characterisation, comparative analysis (agronomic, phenotypic and compositional characteristics) and the outcome of the toxicological, allergenicity and nutritional assessment indicate that the combination of the single soybean events and of the newly expressed proteins in the soybean DAS-44406-6 × FG72 does not give rise to food and feed safety or nutritional concerns. The GMO Panel concludes that the DAS-44406-6 × FG72 stack soybean, as described in this application, is as safe as the non-GM comparator and non-GM reference varieties tested, and no post-market monitoring of food and feed is considered necessary. In the case of release of processed soybean DAS-44406-6 × FG72 or accidental spillage of viable GM soybean seeds into the environment, this would not raise environmental safety concerns. The post market environmental monitoring plan and reporting intervals are in line with the intended uses of soybean DAS-44406-6 × FG72. The GMO Panel concludes that soybean DAS-44406-6 × FG72 is as safe as its non-GM comparator and the tested non-GM reference varieties with respect to potential effects on human and animal health and the environment.